Valium or Diazepam
Valium is an anxiolytic drug (tranquilizer), characterized by sedative, anticonvulsant, hypnotic and miorelaxing action.
ATX Code: N05BA01
Active ingredient: Diazepam
Manufacturer: Hoffmann-La Roche Ltd. (Switzerland)
Indications for use
Valium is prescribed for conditions such as anxiety disorders, insomnia, dysphoria, muscle spasms, spastic conditions caused by damage to the brain or spinal cord (athetosis, tetanus, cerebral palsy).
The drug is used for such diseases: arthritis, bursitis, myositis, Bechterew’s disease, chronic progressive polyarthritis, arthrosis, accompanied by muscular tension of the skeleton, stenocardia, vertebral syndrome, headaches.
Valium ( Diazepam) is indicated for withdrawal symptoms, if the patient is disturbed by tension, tremor, anxiety, or intense agitation.
The drug is included in the complex treatment of such diseases: gastrointestinal ulcer, hypertension, disorders that occur in gynecology and obstetrics (psychosomatic, menstrual and climacteric), epilepsy, infarction, skin diseases, eczema.
With the help of this medication, premedication is performed before diagnostic endoscopic manipulations or operations. The agent is used in obstetric practice: to facilitate labor activity, in case of premature birth (only at the end of the third trimester) and with detachment of the placenta.
Valium ( Diazepam) is contraindicated in the following cases: shock, coma, hypersensitivity, myasthenia gravis, glaucoma, acute alcohol and drug poisoning, acute respiratory failure, chronic obstructive pulmonary disease.
Instructions for use Valium ( Diazepam) (method and dosage)
The dose of Valium is calculated individually depending on the patient’s condition, clinical picture of the disease, sensitivity to the drug.
Tablets are taken orally, from 1 to 3 years – 1 mg, from 3 to 7 years – 2 mg, from 7 years and older – 3-5 mg. Daily doses – 2, 6 and 8-10 mg respectively.
As an anxiolytic drug is prescribed inside, 2.5-10 mg Valium 2-4 times a day.
Psychiatry: with neuroses, hysterical or hypochondriacal reactions, states of dysphoria of different genesis, phobias – 5-10 mg 2-3 times a day. If necessary, the dose may be increased to 60 mg / day. With alcohol withdrawal syndrome – 10 mg 3-4 times a day in the first 24 hours, followed by a decrease to 5 mg 3-4 times a day.
Neurology: spastic conditions of central origin in degenerative neurological diseases – inside, 5-10 mg 2-3 times a day.
Cardiology and rheumatology: stenocardia – 2-5 mg Valium 2-3 times a day; arterial hypertension – 2-5 mg 2-3 times a day, vertebral syndrome with bed rest – 10 mg 4 times a day; as an additional drug in physiotherapy with rheumatic pelviscandiloarthritis, progressive chronic polyarthritis, arthrosis – 5 mg 1-4 times a day.
Obstetrics and gynecology: psychosomatic disorders, climacteric and menstrual disorders, gestosis – 2-5 mg 2-3 times a day. Pre-eclampsia – the initial dose – 10-20 mg IV, then 5-10 mg orally 3 times a day; eclampsia – during the crisis – in / in 10-20 mg, then if necessary in / in a jet or drip, not more than 100 mg / day. With the purpose of facilitating the labor activity when opening the cervix for 2-3 fingers – in / m 20 mg; with premature birth and premature detachment of the placenta – in / m in an initial dose of 20 mg, after 1 h the administration of the same dose is repeated; maintenance doses – from 10 mg 4 times to 20 mg 3 times a day. With a premature detachment of the placenta, the treatment is carried out without interruptions – until the fetus ripens.
Parenteral, epileptic status and severe recurrent epileptic seizures: children from 30 days to 5 years of age – slowly (slowly) 0.2-0.5 mg every 2-5 minutes to a maximum dose of Valium 5 mg, 5 years and older – 1 mg every 2 -5 minutes to the maximum dose of 10 mg; if necessary, the treatment can be repeated after 2-4 hours. Muscle relaxation, tetanus: children from 30 days to 5 years – in / m or / in 1-2 mg, 5 years and older – 5-10 mg, if necessary, the dose can be repeated every 3-4 hours.
When motor excitation is administered in / m or iv 10-20 mg 3 times a day. In case of traumatic spinal cord injuries accompanied by paraplegia or hemiplegia, chorea is given to adults in the initial dose of 10-20 mg, children – 2-10 mg.
With epileptic status – IV in the initial dose Valium ( Diazepam) 10-20 mg, then, if necessary – 20 mg IM or IV drop.
For relief of severe muscular spasm – iv once or twice 10 mg. Tetanus: the initial dose is 0.1-0.3 mg / kg IV at intervals of 1-4 hours or as an iv infusion of 4-10 mg / kg / day.
- At the beginning of therapy Valium can cause the following side effects:
- drowsiness and lethargy;
- increased fatigue;
- poor coordination of movements;
- retrograde amnesia and worsening attention;
- slowing of motor and mental reactions.
In rare cases, a tranquilizer can cause such side effects:
- euphoria, excitement;
- tremor, weakness, anxiety;
- headache, confusion;
- depression, fear;
- muscle spasms;
- irritability, insomnia;
- violation of hematopoiesis (neutropenia, anemia, etc.);
- dyspeptic disorders (dry mouth, nausea, vomiting, constipation, etc.);
- disorders of the CAS (tachycardia, hypotension);
- impaired kidney function;
- increased or decreased libido, dysmenorrhea;
- allergic reactions.
- Valium can cause an addictive effect.
In case of an overdose, there is an increase in side effects, up to coma. In this case, it is necessary to induce vomiting, to carry out detoxification activities with subsequent washing of the stomach.
Analogues according to the ATC code: Diazepam, Apaurin, Diazepabene, Diazeleks.
Do not make the decision to replace the drug yourself, consult a doctor.
Valium ( Diazepam) lowers blood pressure, increases the pain threshold, dilates blood vessels, reduces painful seizures (paroxysms), reduces the production of gastric juice at night.
The drug begins to act only on the 2-7th day of therapy. In people suffering from arrhythmia, cardialgia and paresthesia, the positive effect of the drug is observed 7 days after the start of treatment.
In the case of abstinence syndrome, which occurs in chronic alcoholism, this tranquilizer helps to weaken manifestations of tremor, agitation, eliminates hallucinations and delirium (mental disorder, in which there is a violation of consciousness).
The drug is prescribed exclusively by the attending physician. To buy Valium without a prescription and to accept without preliminary consultation with the expert is strictly forbidden.
To prevent an overdose, barbiturates should be taken. Before taking it, you should consult your doctor.
At pregnancy and thoracal feeding
During pregnancy and lactation, Valium ( Diazepam) is strictly prohibited.
Children older than 6 months may be prescribed a drug for psychosomatic and reactive disorders, as well as for epilepsy. Dosage is determined by the attending physician, depending on the age and condition of the patient.
In old age
The elderly should take the drug with caution. At the beginning of the course of therapy, the daily dosage should not exceed 4 mg.
Valium leads to the potentiation of the effects of alcohol, anticonvulsant, hypnotics, antihistamines and hypotensive drugs, antipsychotics, tricyclic antidepressants, general anesthetics, muscle relaxants and analgesics.
In combination with analeptics and psychostimulants, Diazepam loses its activity.
Antacids reduce the rate of absorption of the active substance.
Terms and conditions of storage
Keep out of the reach of children at temperatures not exceeding + 30 ° C. Shelf life of tablets is 5 years, solution for injection – 4 years.
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